Blar i forfatter "Grip, Jostein"

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    • Beta-glucan-loaded nanofiber dressing improves wound healing in diabetic mice 

      Grip, Jostein; Engstad, Rolf Einar; Skjæveland, Ingrid; Skalko-Basnet, Natasa; Isaksson, Johan; Basnet, Purusotam; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-01)
      The increased prevalence of chronic wounds requires novel treatment options. The aim of this study was to develop a beta-glucan (βG)-loaded nanofiber wound dressing. Nanofibers were prepared using the needle-free Nanospider™ technology, an electrospinning method which enables the production of nanofibers at an industrial scale. The βG was selected as active ingredient based on its confirmed wound ...

    • Development of a novel beta-glucan supplemented hydrogel spray formulation and wound healing efficacy in a db/db diabetic mouse model 

      Grip, Jostein; Steene, Erik; Engstad, Rolf Einar; Hart, Jeff; Bell, Andrea; Skjærveland, Ingrid; Basnet, Purusotam; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-30)
      To relieve the severe economic and social burdens and patient suffering caused by the increasing incidence of chronic wounds, more effective treatments are urgently needed. In this study, we focused on developing a novel sprayable wound dressing with the active ingredient β-1,3/1,6-glucan (βG). Since βG is already available as the active ingredient in a commercial wound healing product provided as ...

    • Polymere partikler som vaksinebærere i atlantisk laks (Salmo salar): en studie av antistoffrespons og depoteffekt ved bruk av partikler med ulik størrelse, molekylvekt og L:G forhold. 

      Grip, Jostein (Master thesis; Mastergradsoppgave, 2011-06-14)
      Sammendrag Partikler av polymerene poly (lactide-co-glycolide) acid (PLGA) og poly (lactide) acid (PLA) har vist seg å være effektive som adjuvanter/antigendepot i musemodeller, hvor de bidrar til å fremprovosere en robust og vedvarende antistoffrespons. Fremdeles er PLGA/PLA-partiklenes egenskaper som adjuvans i atlantisk laks lite kjent. Målet med dette studiet var å sammenlikne depotegenskapen ...

    • Sprayable Carbopol hydrogel with soluble beta-1,3/1,6-glucan as an active ingredient for wound healing – Development and in-vivo evaluation 

      Grip, Jostein; Engstad, Rolf Einar; Skjærveland, Ingrid; Skalko-Basnet, Natasa; Holsæter, Ann Mari (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-21)
      Chronic wounds represent a significant health problem worldwide. There is a need for advanced- and cost-efficient wound healing products able to increase patient comfort and reduce the healing time. The aim of this study was to develop a sprayable hydrogel dressing with beta-glucan (βG) as the active ingredient, targeting future application in the treatment of both chronic and burn wounds. The βG ...